Thursday , January 27 2022

Does glandular fever cause schizophrenia? The research reveals a link


The study has found that uterine fever as a teenager can increase the risk of schizophrenia.

The common virus that spread by kissing was related to psychiatric researchers at John Hopkins University in Baltimore.

People with schizophrenia had more than doubled the rate of glandular fever antibodies.

The scientists who were there found that it could pave the way for the prevention of serious mental disorders.

The study found that glandular fever could increase the risk of schizophrenia

The study found that glandular fever could increase the risk of schizophrenia

The study found that glandular fever could increase the risk of schizophrenia

However, the virus known in the United States as mono cannot be treated and can only be controlled with good hygiene.

It is caused by the EBV or Epstein-Barr virus, which infects more than 90 percent of people worldwide, according to Cancer Research UK.

In most people with the Epstein-Barr virus, it is inactive unless it is active, that is, if it causes glandular fever.

According to the World Health Organization, schizophrenia affects more than 21 million people worldwide.

Researchers are not convinced of the causes and consequences, so it is possible that the link between the two might be the other way around.

"We are interested in the role of infectious agents such as Epstein-Barr virus in schizophrenia," said leading author Professor Roberts Jolken.

The study looked at 743 people – 432 with a diagnosis of schizophrenia and 311 without a history of psychiatric illness that served as a control group.

Researchers first measure the level of EBV antibodies in both study groups published in the Schizophrenia Bulletin.

They found that people with schizophrenia were 1.7 to 2.3 times more likely to have increased levels of some EBV antibodies than in the control group.


Glandular fever mainly affects adolescents and young people. It gets better without treatment, but it can make you feel very sick and last for weeks.

Symptoms include:

  • Very high temperature or heat sensation
  • Swelling on both sides of the neck – swollen glands
  • Extreme fatigue or exhaustion
  • Tonsilite that doesn't stay better

More serious symptoms that may require an emergency are:

You should feel better in two to three weeks. Some people may feel very tired for months.

Glandular fever can cause your spleen to swell. Avoid sports or activities that may increase your risk of falling during the first month, as this may damage your spleen.

You usually do not get gland fever more than once.

Source: NHS

The researchers then concluded part of the participants' DNA to determine their genetic risk to schizophrenia.

The results of the analysis showed that people with an increased risk of schizophrenia and an increased level of antibodies to EBV had more than eight times the chances of being schizophrenic compared to mentally healthy.

Antibodies associated with other viruses, such as chickenpox or cold pain virus, have not increased in people with schizophrenia.

"We discovered that individuals with schizophrenia had an unusual reaction to Epstein-Barr virus," Professor Yolken said.

“It indicated that EBV prevention and treatment could be an approach to the prevention and treatment of serious psychiatric disorders such as schizophrenia.

EBV is not available for treatment procedures approved by the US Food and Drug Administration and the United Kingdom.

According to scientists, several compounds are being investigated that can prevent or treat viral replication and should be a "high priority".

Researchers recommend preventing EBV transmission with good hygiene, hand washing and avoiding mouth contact, such as kissing infected people.

Epstein-Barr is a virus that causes glandular fever or 'mononucleosis / mono', with swollen glands and fatigue.

It affects young people most, going through blood and sperm, and most often saliva – even in the smallest amounts, for example, drinking from the same glass as someone.

Up to seven weeks after the infection, it may not show any symptoms, and the person in life is the carrier of EBV.

EBV has already been linked to MS and cancer, according to UK cancer research, EBV has caused less than one in every 300 UK cases of cancer.

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