They develop an artificial placenta that can explain some problems during pregnancy
On Wednesday, British scientists said they had developed artificial placenta at an early stage, which could serve as an experimental model to understand why some women experience complications or even breaks during pregnancy.
If the placenta does not work properly, it can cause serious problems, such as pre-eclampsia or spontaneous abortion (…) But our knowledge of this important organ is very limited, "said lead author Margherita Turco in a scientific journal Nature.
Usually, medical research first experiments with animals about the treatment potential and reliability of young people. But "human placenta is very different from other species," Ashley Moffett, professor of pathology at the University of Cambridge, who has been working on placental cell culture for more than 30 years, said at a press conference.
His team succeeded in isolating and growing trophoblast cells that formed only a few days after fertilization, and then became a placenta and cranial.
Thus, scientists created what they called "miniplacent", which in vitro reproduces the actual functioning and distributes hormones and proteins that damage the metabolism of women during pregnancy.
They hope that this model will allow you to better investigate anomalies in placenta development that can prevent proper implantation of the embryo or create problems during pregnancy.
According to World Health Organization data, around 47,000 women died in 2015 because of preeclampsia, which is characterized by high blood pressure associated with excessive protein in the urine.
Artificial placenta can also be illuminated by the effect of maternal medications on the placenta and why some infections pass through this natural barrier, such as Zika virus, and others do not work, just like dengue, albeit similar.
Last year, the same Cambridge team managed to restore the uterine mucus culture, tissue that connects the womb's inner wall and implants placenta during pregnancy.