Wednesday , March 22 2023

Restore cells and treat spinal cord injuries with 3D implants


LONDON (EFE). – US scientists have created an implant that promotes cell growth in mice to treat spinal cord injuries with a three-dimensional printer, according to a magazine published study. Nature

Investigations developed by University of California, San Diego (US), improves axonal (communication channel) regeneration techniques between neurons that open the door to new vertebro-medullary problems, the authors point out.

The above-mentioned 3D implant or "scaffolding", as called by experts, mimics the natural anatomy and after "charging" with the nerve stem cells, it is placed in places where serious spinal cord lesions have been detected in rodents.

The subjects to whom this method was applied were popular "Tissue regeneration, stem cell survival, and neuronal stem cell spacing from scaffolding to host spinal cord".

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Near the goal

"In recent years, we have increasingly focused on the global goal of rich and distant rejuvenation of vertebral column, which is the ultimate goal of restoring physical function.", points Mark Tuszynski, co-author of the study.

This quality leap, says his companion Kobi Koffler, has been possible because of the ability of three-dimensional "scaffolding" "Activate spinal cord thin and grouped matrices"Helping "Recovered axons are organized" about "Repeat the brain anatomy"As it was before the injury.

They also highlight the role of high-speed 3D printers in creating implants that mimic nervous system structures.

"Like the bridge, the (scaffolding) lines restore axons from one end of the spinal cord to the other. Axoni can spread and grow in any direction, but the scaffolding keeps it in order to drive it in the right direction to complete the spinal cord connection. Shaochen Chen from UC San Diego Medical Engineering Institute.

Results for people

According to the experts, this process can be repeated on the scale of the human spinal cord, as evidenced by the fact that the four-centimeter implant models were printed from the real spinal injury scanners and only in 10 minutes.

"It shows the flexibility of our 3D printing technology. We can quickly print the implant with the right size to match the area of ​​the spinal cord injury, regardless of size or shape," concludes Wei Zhu, co-author of the study.

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