Four people were taken to the hospital after the fire on the fourth floor of the Birmingham Tower Quarter.
Up to 15 adults and 12 children were evacuated from Wells Tower Ladywood after Blaze broke out in the apartment at about 11:40 PM, fire teams said.
Four of them were treated to affect smoke breathing.
It is believed that the fire was started with smoking materials, such as ejectable cigarettes, by attaching a West Midlands fire service representative.
Five firefighter crew members were sent to the scene to highlight the burner in one apartment.