Now you are following the course "Trypanosoma" and Yasmin Amr's diagnosis method – and now we come to the details
Trypanosomiasis is a monoclonal group of metastatic glandular, parasitic parasitic protozoa, which is part of the sachromastigophora subspecies whose name derives from the Greek word "trypano" and "bag" due to the kinetic movement of the organism. Most species are transmitted by invertebrates that nourish the blood, but there are different mechanisms among the different species, some of which are distributed as tripanosomes in direct contact and are the invertebrate of the Pot, usually the intestine, but usually occupy the blood or the environment of the host's mammalian blood.
What is Trypanosoma?
Trypanosomiasis affects various hosts and causes many diseases including deadly human sleep diseases caused by Prussian trypanosomiasis and Chagas disease caused by trypanosomiasis, and the mitochondrial genome consists of trypanosomiasis and other engines known as kinetic plasma, Very complex chips and small chains requires a group of proteins that regulate cell division.
African trypanosomiasis is diagnosed by laboratory methods because the clinical manifestations of infection are not specific enough and the diagnosis depends on the detection of the parasite in the body's fluid or tissues using a microscope, and the parasitic pregnancy Tb. Rhythmic parasites are easily found in the blood and can also be found in lymph node fluids or biopsy fluids, serological tests are not widely available and are not used in diagnostics, as the microscopic detection of parasites is simple and simple. Gambians are microscopically perfusing the lymph nodes, usually from the cervical background.
Gambia's blood discovery
It is often difficult to determine the level of T.b in the blood, there is an urgent need for a concentration and serial test method, and the serological test is available outside the United States in the case of T. b gambia, but is usually used only for screening purposes and the final diagnosis is based on parasitic microscopic observation. All African tripanosomal patients should be tested for cerebrospinal fluid to determine whether they are involved in the central nervous system, as the choice of medication depends on the stage of the disease. The number of leukocytes is more than 5 and can often be seen in Trypansoma with spinal cord fluid infected with the second phase of humans.
Diagnosis of the stage of illness is a necessary step to complete the diagnosis of HRT, which is necessary for proper treatment, and is provided in two stages: diagnosis must confirm the presence of the parasite in any fluid in the body and usually in the blood and lymphatic system. And also because there is no sensitivity to parasitic methods.
The first stage or the initial stage of lymphocytes develops at the second or brain stage, where the peritoneum invades the central nervous system (CNS). Although the brain brain invasion occurs after 3 to 2 months after the infection, and the two forms of the disease are determined by CSF.
Lumbar puncture is usually done immediately after the parasites have been diagnosed with trypanosomiasis or if there are indications of an infection that justifies this relatively recent intervention (eg, indicative clinical signs or strong serological suspicion), and T. b. Roddis infection is done in practice only after the dose of Soramine at which it is believed that the blood parasites must be cleaned before the lumbar puncture, in order to avoid the parasite entering the CSF in the case of lumbar puncture.
In addition, parasite resistance to existing drugs is always dangerous, and only four medicines are prescribed to treat human African trypanosomiasis, pentamidine, soramine, melarsoprol and epulfurite and to use Fifth drug "nifurtimox" in combination with special licenses, but none of them knows it there is a certain degree of toxicity, and pentamidine and soramine are used in Rhodesian infections at the first or early stages.
Effluorinetin can be used as monotherapy but only in the second phase of tripanosomiasis, as it has not been shown to be effective against the disease since 2009. The combination of Eflornithine and Naporethomics (NECT) is accepted as treatment of first-class Phase II human African trypanosomiasis in all affected countries. The combination of both drugs reduces the duration of monofluorinated therapy and is easier to manage by improving efficiency and safety. The measures and equipment needed to manage it, WHO also trained public employees on how to manage the medicine, and misalarsoprol would treat the last stage of the disease.
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