Sunday , February 28 2021

Breakthrough in Peace Restless Legs Syndrome

New research published Physiology Journal triggers a breakthrough in Restless Legs Syndrome (RLS).

RLS is a common condition of the nervous system, which causes a great irresistible urge to move the legs. Patients complain of unpleasant symptoms, such as tingling, burning and painful leg cramps. More than 80% of people with RLS experience that their feet are uncontrollably jerked or torn, usually at night.

To date, RLS was thought to be caused by genetic, metabolic and central nervous system mechanisms. Researchers for the first time prove that in fact it is not only the central nervous system but also nerve cells that target the same muscles that are responsible.

This new study suggests that RLS forced legs cause increased nerve cells that provide leg muscles to increase dissipation, resulting in increased nerve cell signaling.

The targeting of messages sent between nerve cells to reduce the number of messages to normal levels can help prevent RLS symptoms. This could be achieved with new drugs that block ion channels that are essential for communication between nerve cells.

The study by the University of Gottingen, in collaboration with Sydney University and the University of Vanderbilt, included the excitement of nerve cells in patients with RLS and healthy individuals.

The next step is to investigate the effects of various drugs in patients and the effects on RLS.

The corresponding author of the research, Dirks Češņiks, commented on the findings:

"Patients suffering from Restless Legs Syndrome complain about painful symptoms in their legs that cause sleep disorders. The mechanisms of RLS are still not fully understood. We have shown that nerve cells that supply the muscles in the leg are also responsible, and therefore with these drugs cells may be provided with complementary therapies. "


Disclaimer: AAAS and EurekAlert! are not responsible for the news release of EurekAlert! promotional bodies or use any information through the EurekAlert system.

Source link