Antidepressant fluoxetine (Prozac) is ineffective to treat rare diseases reminiscent of poliomyelitis researchers report that it can cause muscle weakness and paralysis in children.
In the United States, 219 possible cases acute flaccid myelitis (MFA) and 80 are approved, according to the US Disease Control and Prevention Center (CDC). UU
According to the agency's data, in 2014, 120 cases were approved, 22 cases in 2015, 149 cases in 2016 and 33 cases in 2017.
Human cause myelitis acute lean It is not clear, but some patients are infected with a commonly harmless cold virus, called EV-D68.
Researchers have been looking for possible treatments myelitis acute lean. Laboratory tests showed that fluoxetine had an antiviral effect on EV-D68, so some experts suggested that an antidepressant might be possible treatment for the disturbance.
In this study, researchers examined 56 children (30 months to 9 years of age) who were treated with MFA in 12 US medical centers. UU in the period from 2015 to 2016. 28 patients received more than one dose of fluoxetine, but 28 people did not receive this medicine or only received one dose and were considered to have not been treated.
In assessing whether the medicine was effective, muscle strength was assessed in the arms and legs of children.
After an average seven-month follow-up period, the strength indicators on the scale from 0 to 20 were reduced by 0.2 children who received the drug and improved by 2.5, compared to the untreated group.
The findings of the study were published in an online magazine on November 9 Neurology.
"Lack of efficiency signal treatment about acute flaccid myelitis In this study, the evaluator emphasizes the need to develop and evaluate strategies in the future treatment and more effective prevention of this potentially disruptive state, "said Dr. Kevin Messacar of Colorado's Children's Hospital in Aurora, a study published in a magazine issue.
Dr Carlos Pardo-Villamizar, a medical expert at the Johns Hopkins University School of Medicine in Baltimore, told HealthDay News that "we need to pay attention to it, taking into account the long-term consequences that children and their family members have on Parents suffering."
"You can not even imagine how these children live in their lives," he added.