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Adolescent obesity can increase the risk of pancreatic cancer a year later



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HealthDay Reporter

WEDNESDAY, Nov 14, 2018 (HealthDay News). Obesity in adolescents can increase the risk of death of a deadly pancreatic cancer in adulthood, researchers report.

The Israeli team of researchers has found out the prospects for this rare cancer, which could be quadrupled due to obesity. In addition, the risk increases with an increase in body weight, even affecting men in a high normal range of weight.

"It is known that for some time a diet can increase the risk of an individual's risk of developing pancreatic cancer, and [this is] a major new discovery that suggests that obesity and overweight may also be at risk in adolescence, "said Allison Rosenzweig, senior director of the Pancreatic Cancer Network.

But if you are overweight or obese, that does not mean you're sick with the disease, said Rosenzweig, who did not matter in the study.

"Since pancreatic cancer is a relatively rare disease, it's believed that around 55,000 Americans are affected this year, even those who are at increased risk, the development of the disease is unlikely," she said.

Also, because this study looked at retrospective data, it can not prove that overweight is a cause of pancreatic cancer, but it is there.

According to the cancer network, pancreatic cancer is the third leading cause of cancer death in the United States, with a five-year survival rate lower than 10 percent.

Researchers from the Rabin Medical Center in Petah Tikva and at Tel Aviv University collected data from more than 1 million Jewish men and 700,000 Jewish women in Israel for the new study, a new study by Dr. Zohar Levi. From 1967 to 2002, the participants were physically tested between the ages of 16 and 19.

By using the Israeli National Cancer Registry, researchers have identified pancreatic cancer cases by 2012. Their observations revealed 551 new cases of pancreatic cancer.

Compared with normal weight, obesity was associated with a risk of almost four-fold male cancers. Among women, the risk was slightly more than four times higher, researchers discovered.

In general, researchers attracted almost 11% of the cases of pancreas due to overweight and obesity.

The report was published on November 12th in the journal Cancer.

Dr. Chanan Meydan of the Mayanei Hayeshua Medical Center in Israel wrote an addendum to the study. He said weight gain in teenage years could increase inflammation that damages cells and can increase the risk of cancer.

"It would be interesting to find out if the inflammatory process caused by obesity is related to the malignant tumor's inflammation process. Are they somehow linked?" said Meidan.

The anti-inflammatory mechanism "is largely a delicately balanced phenomenon with severe consequences when it's not in balance," he said.

Learning more about how this "control switch" works can help scientists better understand the relationship between obesity and cancer, Meydan added.

More information

The US State Cancer Institute has more than pancreatic cancer.

SOURCE: Chanan Meydan, M.D., Mayanei Hayeshua Medical Center, Bnei Braka, Israel; Allison Rosenzweig Ph.D., Senior Manager, Scientific and Clinical Communication, Pancreatic Cancer Action Network; November 12, 2018 Canceronline

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