Monday , April 19 2021

They create a gel that can prevent the spread of cancer



United States of America

Research team from the University of California, UCLA, United States has created a biodegradable aerosol gel with medicines that improve the immune system have prevented the spread of cancer laboratory animals and prevents it from spreading to other parts of the body.

Aerosol not only prevents tumor reps in the body from which they are produced, but also "controls the development of tumors in other parts of the body," says Zhen Gu, a research director at the Engineering School at Samuel University of UCLA and Zhen Gu, a member of the Jonsson All-Cancer Center at the same university.

Study has shown that many people who have cancer will undergo some kind of surgery to treat the disease, Almost 95 percent of patients with breast cancer Early diagnosis requires surgery, and in general it is the first line of treatment for people with brain tumors. But, "despite the improvements in the last decade of surgical techniques, cancer often returns to the procedure," they warn from UCLA.

Researchers they tested gel in mice that had progressive tumors of the melanoma is surgically removed, if used, will reduce the growth of the tissue cells that remained after surgery, helping to prevent relapse of the cancer. After receiving the treatment, 50% of the mice survived for at least 60 days, without the recovery of their tumors.

Around 90 percent of people with cancerous tumors eventually die due to a tumor's recurrence or metastasis, Explain from UCLA. Therefore, says Gu, "this sprayer is promising against one of the biggest barriers to cancer treatment."

Researchers loaded nanoparticles with a targeted antibody to block CD47, a protein that is caused by cancer cells. By blocking CD47, the antibody allows the immune system to be found and ultimately destroys cancer cells.

The nanoparticles are made of calcium carbonate, a component that can gradually dissolve in surgical wounds and increase the activity of macrophage type that "helps to remove foreign bodies from the body", following the Gua laboratory postgraduate study and lead author Qian Chen.

It was also noted that gel can activate T cells in the immune system to work with another line of attack against persistent cancer cells, "explains Chen. To use it, this substance will need to undergo more testing and approval. For humans, they report from UCLA.

With information from Europa Press

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