Researchers have been successful in developing "mini-placenta" or placental organo-laboraits that could transform pregnancy, conception, mortality, spontaneous abortion, and pregnancy-related diseases and disorders.
The results of the study on the development of these organoids have been published in the latest edition of the magazine Nature.
These organs can successfully mimic the placenta during the first few months of the first trimester, explaining the researchers. This means that you can investigate the drugs or diseases that affect the placenta at this stage and cause spontaneous abortions. In fact, these small placenta are just about the real placenta that they can also check the positive pregnancy test that the team explains. Ashley Moffett, a senior researcher at the team and professor of reproductive immunology at the University of Cambridge, confirmed this statement: "If we put a pregnant stick in the environment from the organs that it says," pregnant woman. ""
The team explains that the study of placenta in the womb has been uncomfortable until now. A healthy placenta develops and attaches to the uterine walls, and nutrients and oxygen-containing blood supply to the growing embryo and fetus. This not only eliminates hormones and chemicals that allow the fetus to grow, but also destroys growth-induced waste. Placenta also secures hormones in the mother's bloodstream, which helps you to successfully get pregnant. This phenomenon can not be studied by humans so far. With the development of organs, researchers can now understand plasma functions and activities. Moffett said: "Now we can start experimenting with how the placenta develops in the womb environment."
The team used cells from the placenta tissue inflammation. These wools are the usual placenta hair structures. These placental cells grown in a laboratory can be arranged in multiple cell groups or structures that can act as a real placenta by secreting proteins and hormones. They range from a tenth of millimeters to half a mile and can be stored frozen only before use.
The submitted experts commended this study and said that it would provide an invaluable insight into the common problems with pregnancy, including births, growth retardation in the womb (IUGR) and preeclampsia. One could also investigate if they have feline infections like Zika and how they affect development and growth.
The research leader Margherita Turco said: "Placenta is absolutely necessary to support the baby as it grows up in the mother's womb. If it does not work properly, it can cause serious problems, from preeclampsia to miscarriage, with immediate and lifelong consequences for both mother and baby. "The team adds that the testing of teratogenic drugs or drugs could be invaluable for the unborn child when used for the mother. Placental organs are also a source of stem cell therapy in the event of pregnancy or threatened pregnancy explained by the team. In short, pregnancy studies have several uses of these organoids.
According to Moffett, "To reach this point has been needed over a period of 30 years, and although we know that the microplate we know will grow in the laboratory for at least one year."
Published: Medical research news Women's Health News